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University of Connecticut - Quest Portal

Immune Tolerance Network (UM1 Clinical Trial Required)
Deadline Nov 9 2026 12:00 PM (EST)
Description

National Institutes of Health (NIH)


Limited Submission Process Overview

The Office of the Vice President for Research (OVPR) is pleased to announce this limited submission funding opportunity/award. Limited submission programs restrict the number of applications an institution may submit to the sponsor.


All interested PIs must submit a Notice of Intent (NOI) through the UConn Quest Portal by the deadline listed below to be considered.


After the NOI deadline, OVPR will determine whether an internal competition is needed based on the number of NOIs received. If the number of NOIs does not exceed the sponsor’s limit, eligible PIs who submitted an NOI by the deadline are typically approved to move forward without an internal competition. If no NOIs are received, the opportunity may remain open on a first-come, first-served basis until all available slots are filled or the sponsor deadline passes, whichever comes first (see full process on our website).

                                                                                                                                     

Key Deadlines

Deadline

Date/Time

Notes

Internal NOI Deadline

Monday, 11/9/2026 by 12 noon

Required.

Internal Pre-proposal Deadline

Monday, 11/23/2026 by 12 noon

Only required if an internal competition is needed.

Sponsor Full Proposal Deadline

1/29/2027, 5 p.m. ET


Opportunity Quick Reference

Item

Details

Program Link

https://www.grants.gov/search-results-detail/362946 

Quest Portal Link

https://quest.uconn.edu/prog/ITN_FY27 

Award Details

Application budgets are not expected to exceed $23M/year in direct costs for 7 years.

Number of UConn Applicants Allowed

1 UConn – 1 UCH

Funding Opportunity Description

Program Description

This NOFO will support a cross-disciplinary consortium responsible for conducting research in three areas of immune-mediated conditions. Input from clinicians and immunologists, both within and outside the Network, will be important toward the design, development, and conduct of clinical trials and integrated mechanistic studies. The three clinical areas, along with examples of high-priority research topics, include:

  1. Allergic diseases and asthma;
  2. Autoimmune diseases; and
  3. Immune-mediated consequences of transplantation. 


The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.

FAQ and Additional Information

Question

Answer

What happens after the NOI deadline?

After the NOI deadline, one of three outcomes typically applies.

  1. If the number of NOIs received exceeds the sponsor’s limit, OVPR will conduct an internal competition. 
  2. If the number of NOIs does not exceed the sponsor’s limit, eligible PIs who have submitted an NOI by the deadline are typically approved to move forward without an internal competition. If any slots remain available, the opportunity will remain open on a first-come, first-served basis.
  3. If no NOIs are received by the deadline, the opportunity will remain open on a first-come, first-served basis until all available slots are filled or the sponsor deadline passes, whichever comes first.


Only PIs selected and approved by OVPR are eligible to submit to the sponsor.

What are the pre-proposal requirements?

If an internal competition is necessary, pre-proposals should include:

  1. Maximum two-page summary describing the project and demonstrating how it will fulfill the program/solicitation criteria and contribute to meeting the research/education goals of the institution (if applicable).
  2. A brief budget overview and justification, 1-2 pages.
  3. Biosketches or CVs for all key personnel.


Please see the sponsor’s guidelines for details about program goals and application components.

What happens after the pre-proposal is submitted? 

  1. Pre-proposals are reviewed by an ad hoc faculty committee with expertise in grant submission and relevant research areas. External reviewers may be involved when necessary.
  2. After selections are made, all applicants will receive notification of the results (and reviewer feedback, when available) at the conclusion of the review.
  3. Selected investigators will be approved to complete and submit full proposals according to the sponsor’s guidelines.

Where can I find more information?

For more information about the limited submission process, please visit our FAQ page.

For additional assistance, please contact us at research@uconn.edu.

How can I stay connected with UConn Research?

Follow UConn Research on Instagram & LinkedIn for all the latest information.


Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application.  Before proceeding with your submission, please review their terms and privacy statements linked below.

Immune Tolerance Network (UM1 Clinical Trial Required)


National Institutes of Health (NIH)


Limited Submission Process Overview

The Office of the Vice President for Research (OVPR) is pleased to announce this limited submission funding opportunity/award. Limited submission programs restrict the number of applications an institution may submit to the sponsor.


All interested PIs must submit a Notice of Intent (NOI) through the UConn Quest Portal by the deadline listed below to be considered.


After the NOI deadline, OVPR will determine whether an internal competition is needed based on the number of NOIs received. If the number of NOIs does not exceed the sponsor’s limit, eligible PIs who submitted an NOI by the deadline are typically approved to move forward without an internal competition. If no NOIs are received, the opportunity may remain open on a first-come, first-served basis until all available slots are filled or the sponsor deadline passes, whichever comes first (see full process on our website).

                                                                                                                                     

Key Deadlines

Deadline

Date/Time

Notes

Internal NOI Deadline

Monday, 11/9/2026 by 12 noon

Required.

Internal Pre-proposal Deadline

Monday, 11/23/2026 by 12 noon

Only required if an internal competition is needed.

Sponsor Full Proposal Deadline

1/29/2027, 5 p.m. ET


Opportunity Quick Reference

Item

Details

Program Link

https://www.grants.gov/search-results-detail/362946 

Quest Portal Link

https://quest.uconn.edu/prog/ITN_FY27 

Award Details

Application budgets are not expected to exceed $23M/year in direct costs for 7 years.

Number of UConn Applicants Allowed

1 UConn – 1 UCH

Funding Opportunity Description

Program Description

This NOFO will support a cross-disciplinary consortium responsible for conducting research in three areas of immune-mediated conditions. Input from clinicians and immunologists, both within and outside the Network, will be important toward the design, development, and conduct of clinical trials and integrated mechanistic studies. The three clinical areas, along with examples of high-priority research topics, include:

  1. Allergic diseases and asthma;
  2. Autoimmune diseases; and
  3. Immune-mediated consequences of transplantation. 


The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.

FAQ and Additional Information

Question

Answer

What happens after the NOI deadline?

After the NOI deadline, one of three outcomes typically applies.

  1. If the number of NOIs received exceeds the sponsor’s limit, OVPR will conduct an internal competition. 
  2. If the number of NOIs does not exceed the sponsor’s limit, eligible PIs who have submitted an NOI by the deadline are typically approved to move forward without an internal competition. If any slots remain available, the opportunity will remain open on a first-come, first-served basis.
  3. If no NOIs are received by the deadline, the opportunity will remain open on a first-come, first-served basis until all available slots are filled or the sponsor deadline passes, whichever comes first.


Only PIs selected and approved by OVPR are eligible to submit to the sponsor.

What are the pre-proposal requirements?

If an internal competition is necessary, pre-proposals should include:

  1. Maximum two-page summary describing the project and demonstrating how it will fulfill the program/solicitation criteria and contribute to meeting the research/education goals of the institution (if applicable).
  2. A brief budget overview and justification, 1-2 pages.
  3. Biosketches or CVs for all key personnel.


Please see the sponsor’s guidelines for details about program goals and application components.

What happens after the pre-proposal is submitted? 

  1. Pre-proposals are reviewed by an ad hoc faculty committee with expertise in grant submission and relevant research areas. External reviewers may be involved when necessary.
  2. After selections are made, all applicants will receive notification of the results (and reviewer feedback, when available) at the conclusion of the review.
  3. Selected investigators will be approved to complete and submit full proposals according to the sponsor’s guidelines.

Where can I find more information?

For more information about the limited submission process, please visit our FAQ page.

For additional assistance, please contact us at research@uconn.edu.

How can I stay connected with UConn Research?

Follow UConn Research on Instagram & LinkedIn for all the latest information.


Submissions to this program are made via a third-party software application, SurveyMonkey Apply. The terms of use and privacy statements for this software apply to your use of it and to the information you provide in your application.  Before proceeding with your submission, please review their terms and privacy statements linked below.

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Deadline
Nov 9 2026 12:00 PM (EST)